Bilimsel Gündem

Sex differences in out-of-hospital cardiac arrest across age groups(yeni sekmede açılır)

Lavignasse, D., Menant, E., Sideris, G., Lemoine, S., Bougouin, W., Beganton, F., Jabre, P., Loeb, T., Agostinucci, J.-M., Lecarpentier, E., Jost, D., Cariou, A., Empana, J.-P., Jouven, X.

Background Sex differences in out-of-hospital cardiac arrest (OHCA) have been studied in adults but remain poorly explored in younger populations. We aimed to assess sex differences in OHCA across age groups to provide a comprehensive overview. Methods All OHCA occurring between May 2011 and December 2018 in Paris and…

Transcatheter aortic valve degeneration: a combined clinical and translational perspective(yeni sekmede açılır)

Yoon, J., Liabot, Q., Jamieson, C., MacLeod, B., Meier, D., Sellers, S. L.

As transcatheter aortic valve implantation (TAVI) is increasingly used in younger and lower-risk patients, long-term valve durability has become a growing concern. Bioprosthetic valve degeneration (BVD) is multifactorial, encompassing calcific and non-calcific structural deterioration, non-structural deterioration,…

Impact of diabetes on outcomes in hypertrophic cardiomyopathy: a GRADE meta-analysis(yeni sekmede açılır)

Mirzohreh, S.-T., Deravi, N., Javanshir, E., Asghari Jafarabadi, M., Roshanravan, N.

Background Diabetes mellitus (DM) is a common comorbidity in hypertrophic cardiomyopathy (HCM) and may exacerbate arrhythmic risk, promote structural remodelling and worsen heart failure outcomes. Its overall prognostic impact and effect on cardiac structure and function in adults with HCM remain uncertain. Method We…

Extending coronary physiology beyond the cath lab(yeni sekmede açılır)

Eftekhari, A.

Coronary computed tomography angiography (CTA), initially adopted as a rule-out modality for obstructive coronary artery disease, has undergone a marked evolution. Increasingly, CTA is used to guide downstream management through integrated anatomical assessment, plaque characterisation and non-invasive physiology via…

Non-specific ECG ST-T abnormalities: cardiac repolarisation memory assessment(yeni sekmede açılır)

Tereshchenko, L. G.

In this issue of the journal, Shoji et al showed that isolated non-specific ST-segment and T-wave abnormalities (NSSTTAs) are associated with incident heart failure (HF). 1 The authors conducted a large prospective general population cohort study of more than 30 000 African-American and white participants aged ≥45…

Effect of pictorial-based information about atherosclerosis on adherence to lifestyle recommendations: results from the VIPVIZA randomised controlled trial(yeni sekmede açılır)

Wennstig, A. C., Själander, S., Hult, A., Liv, P., Norberg, M., Wennberg, M., Wester, P., Wennberg, P.

Aim Low adherence to a healthy lifestyle constitutes a major barrier to effective prevention of cardiovascular disease. We aimed to investigate the effect of pictorial-based information about subclinical atherosclerosis on adherence to health-promoting lifestyle recommendations. Methods Visualization of Asymptomatic…

Development and validation of a nomogram predicting all-cause mortality for patients with an implantable cardioverter defibrillator(yeni sekmede açılır)

Zhou, B., Ding, L., Sun, X., Zhao, S., Chen, K., Su, Y., Yang, J., Liang, Z., Xu, W., Zhang, D., Li, T., Liu, J., Hua, W., Tang, M., Liao, Z., Zhang, S.

Background For patients with a high risk of sudden cardiac death, despite the benefits of an implantable cardioverter defibrillator (ICD), some patients are still at high risk of death. Aim The purpose of this study was to develop and validate a nomogram predicting all-cause mortality for patients with an ICD. Methods…

Coffee may protect your heart but energy drinks could harm it(yeni sekmede açılır)

For most adults, a daily caffeine habit may be safer for the heart than many people assume. A new American Heart Association review found that up to 400 milligrams of caffeine a day, roughly three to five cups of regular black coffee, is generally safe and may even be linked to lower risks of heart disease, stroke,…

Pre-admission statins and circulatory collapse at hospital arrival in ST-segment elevation myocardial infarction(yeni sekmede açılır)

Morikawa, S., Kato, H., Takahashi, N., Ohinata, R., Sato, Y., Mishina, T., Iwata, K., Inoue, N., Takayama, Y.

Background Circulatory collapse at hospital arrival represents one of the most severe clinical presentations of ST-segment elevation myocardial infarction (STEMI) and is associated with poor prognosis. Statins exert pleiotropic effects beyond lipid-lowering, including anti-inflammatory, endothelial, microvascular and…

Reduced cardiac workload and enhanced oxygen extraction during maximal exercise in recreational endurance runners(yeni sekmede açılır)

Kocic, A., Ristanovic, L., Mirkovic, S., Macura, M., Seman, S., Ilic, V., Labudovic, D., Mrdakovic, V., Jakovljevic, S., Bubanj, S., Okwose, N. C., Jakovljevic, D., Stojiljkovic, S.

Background This study assessed cardiac performance in response to maximal physiological stress in recreational long-distance runners. Methods In this cross-sectional observational study, 44 male recreational long-distance runners (age 32.6±8.8 years; body mass index 23.4±2.2 kg/m²) and 41…

Percutaneous coronary interventions improve phasic cardiac-coronary interaction in chronic coronary syndromes as assessed by wave intensity analysis(yeni sekmede açılır)

Tas, A., Alan, Y., Ozcan, A., Kara Tas, I., Tas, N., Sezer, I., Hoef, T. P. v. d., Parker, K. H., Sezer, M., Piek, J. J.

Background Clinical benefit of percutaneous coronary intervention (PCI) in chronic coronary syndromes (CCS) remains controversial. Coronary wave intensity analysis (WIA) provides mechanistic insights into cardiac–coronary coupling. Objectives To assess peri-PCI WIA changes at rest and during hyperaemia, and to…

Comparative performance of stroke risk scores in patients with atrial fibrillation with low stroke risk(yeni sekmede açılır)

Zubrzycki, N., Hyun, K., Teber, E., Farzaneh, B., Ng, A. C. C., Freedman, B., Brieger, D. B.

Background Australian guidelines recommend the CHA 2 DS 2 -VA (congestive heart failure, hypertension, age ≥75 years (double weight), diabetes mellitus, previous stroke (double weight), vascular disease, age 65–74 years) score to identify patients with atrial fibrillation (AF) at low stroke risk who should…