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DİKA — Dijital Kardiyoloji Derneği

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Bilimsel Gündem

Uluslararası kardiyoloji dergileri ve kılavuz kaynaklarından derlenen içerikler, yayın kurulu onayından sonra yayımlanır.

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Frontiers in Cardiovascular Medicine

Genetic liability to childhood Kawasaki disease and adult cardiovascular outcomes(yeni sekmede açılır)

Mengzhuo Wang, Sha Lin, Xiaoliang Liu, Jinlin Wu, Yifei Li

BackgroundKawasaki disease (KD) occurring in childhood has been epidemiologically associated with increased adult cardiovascular risk, particularly in children who develop coronary aneurysms during the acute phase. However, the causal nature of this association remains uncertain. This study employed genetic causal…

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Frontiers in Cardiovascular Medicine

Case Report: Discordant high-sensitivity cardiac troponin T elevation in polymyositis: a diagnostic pitfall(yeni sekmede açılır)

Shuanglin Zheng, Huabin Xie

BackgroundHigh-sensitivity cardiac troponin T (hs-cTnT) is widely used as a gold-standard marker of myocardial injury, yet non-ischemic elevations can occur in idiopathic inflammatory myopathies (IIM), creating a significant diagnostic pitfall. In contrast, high-sensitivity cardiac troponin I (hs-cTnI) generally…

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Frontiers in Cardiovascular Medicine

Is the Cally index truly a prognostic marker that predicts mortality in older patients with acute coronary syndrome?(yeni sekmede açılır)

Ebru Serin, Mert Sarılar, Sinan Şahin, Arzu Er Kara, Hasan Değirmenci, Erol Kalender, Ahmet Gürdal, Kudret Keskin

BackgroundThe C-reactive protein (CRP) -albumin- lymphocyte (CALLY) index has recently emerged as a promising prognostic marker, which reflecting inflammatory, nutrional and immunological statuses. However, no study has reported the prognostic value of the CALLY index in older patients with acute coronary syndrome…

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Frontiers in Cardiovascular Medicine

Metabolic reprogramming in radiation-induced heart disease: the emerging role of PET imaging(yeni sekmede açılır)

Yifan Zhao, Jia Li, Shihao Huangfu, Feiyu Wang, Sanlin Wang, Bingpan Wang, Yanxia Zhang, Caixia Jin, Tianyi Wang, Zijian Wang, Jun Wu

Radiation therapy is widely used to treat various cancers, but it can lead to radiation-induced heart disease, which is the main cause of long-term morbidity and mortality in cancer survivors. Traditional imaging methods, such as echocardiography and cardiac magnetic resonance, often find structural or functional…

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Frontiers in Cardiovascular Medicine

Realistic anatomical model reconstruction and high-fidelity flow computation in stented coronary arteries for the analysis of in-stent thrombosis(yeni sekmede açılır)

Ryo Torii, Amear Mohammed, Mazen Abou Gamrah, Ibrahim Halil Tanboga, Zaid A. Abdulelah, Anantharaman Ramasamy, Thamil Kumaran S. M., Tingquan Zhou, Xingwei He, Tom Crake, Janna Leung, Hui Ying Ang, Nicolas Foin, Jaryl Ng, Shawn Lian Shaoliang, Pieter Kitslaar, Jouke Dijkstra, James Moon, Andreas Baumbach, Christos V. Bourantas

Background and aimsThis article aims to develop and validate a methodology for realistic anatomical reconstruction of stented segments from optical coherence tomography (OCT) and angiographic images and the computation of local haemodynamic forces using computational fluid dynamics, towards a more realistic…

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Frontiers in Cardiovascular Medicine

Pathological mechanisms of inflammatory responses in atherosclerosis and the multi-target regulatory effects of traditional Chinese medicine(yeni sekmede açılır)

Le Zhang, Zihan Chang, Aiying Li, Haijun Wang, Yu Liu

Atherosclerosis (AS) is a vascular disease characterized by chronic inflammation and represents a major pathological basis for cardiovascular events such as myocardial infarction and ischemic stroke. During disease initiation and progression, endothelial dysfunction, lipid retention, sustained recruitment of immune…

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Frontiers in Cardiovascular Medicine

Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan(yeni sekmede açılır)

Mukhammad Komil ogli Amonov

Essential hypertension is a leading cause of chronic kidney disease, but conventional renal markers detect injury only after substantial nephron loss. Urinary nephrin, a slit-diaphragm protein released during podocyte injury, has been proposed as an early biomarker of hypertensive nephropathy, yet stage-specific data…

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Frontiers in Cardiovascular Medicine

Five-year cardiovascular outcomes across hypertensive disorders of pregnancy subtypes: a propensity-matched analysis(yeni sekmede açılır)

Laith Alhuneafat, Omar Obeidat, Dina Mohammed, Nikita Sumzin, Kamel Ikbariah, Ahmad Al-Abdouh, Ahmad Jabri, Bhavadharini Ramu, Jessica Schultz, Jessica Gottula, Bethany A. Sabol, Selma Carlson

BackgroundHypertensive disorders of pregnancy (HDP) are established risk factors for future cardiovascular disease, yet long-term cardiovascular risk across specific HDP subtypes remains incompletely defined.MethodsWe conducted a retrospective cohort study using a large, global electronic health record network to…

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Frontiers in Cardiovascular Medicine

A deep learning model for the interpretable identification of pulmonary thromboembolism from computed tomography pulmonary angiography(yeni sekmede açılır)

Yemei Li, Sunyu Chen, Guangkun Chen, Baosheng Ren, Shibing Hu, Min Zong, Zhongzhi Jia, Tongqing Xue, Ganzhu Feng, Dancen Li

ObjectiveThe rapid identification of pulmonary thromboembolism (PTE) on computed tomography pulmonary angiography (CTPA) is vital but labor-intensive, often leading to diagnostic delays. We aimed to construct and evaluate a YOLOv11 object detection algorithm capable of automatically highlighting intraluminal filling…

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Frontiers in Cardiovascular Medicine

Clinical relevance of circulating endocan and endoglin in excess body weight-associated endothelial dysfunction(yeni sekmede açılır)

Charu Sharma, Abubaker Suliman, Ali Mohammed Aldhaheri, Saeed Mohammed Alnuaimi, Khaled Mohamed Alderei, Sania Mazin AlHamad, Javed Yasin Pathan, Elhadi H. Aburawi

IntroductionEndothelial dysfunction is an early and pivotal event in the development of cardiovascular disease and a key mechanism linked to atherosclerotic plaque formation. Endocan and endoglin are emerging cardiometabolic markers and novel endothelial mediators that promote vascular smooth muscle cell proliferation…

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Frontiers in Cardiovascular Medicine

Interpretable machine learning and mendelian randomization identify risk factors for lower extremity arterial embolism and thrombosis(yeni sekmede açılır)

Xiaodong Li, Guohao Wei, Rui Liu, Qiulin Jiang, Yarong Ma, Xiaolei Sun

BackgroundLower extremity arterial embolism and thrombosis lead to significant morbidity, but their risk factors are not fully characterized.ObjectivesTo identify risk factors and develop an interpretable machine learning (ML) model for predicting lower extremity arterial embolism and thrombosis, with validation using…

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Frontiers in Cardiovascular Medicine

Case Report: Shared decision-making in severe rheumatic mitral stenosis complicating pregnancy(yeni sekmede açılır)

Luis Armando Velásquez Trujillo, Manuel Alejandro Hurtado Rivera, Víctor Rafael Bucheli Enríquez, Sebastián Ayala Zapata, Stephany Barbosa Balaguera, Álvaro Andrés Herrera Escandón

Severe rheumatic mitral stenosis (MS) is one of the highest-risk valvular lesions in pregnancy, and it becomes particularly hard to manage when the valve is unsuitable for percutaneous balloon mitral valvuloplasty (PBMV) and the patient declines termination. We describe a 20-year-old primigravida who presented at 23.5…